Necrobiotic Xanthogranuloma Treated With Topical Nitrogen Mustard (Mechlorethamine)
نویسندگان
چکیده
منابع مشابه
Periorbital necrobiotic xanthogranuloma treated successfully with novel multiple myeloma therapy.
A 46-year-old woman with a medical history of a multinodular goiter presented to the department of dermatology with extensive yellow papules and nodules surrounding both eyelids that had developed over the past 3 years. A skin biopsy was done that showed chronic granulomatous dermal inflammation and foreign body giant reaction consistent with juvenile xanthogranuloma after ruling out a ruptured...
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Necrobiotic xanthogranuloma is a rare, idiopathic, and chronic systemic granulomatous disorder that is usually associated with paraproteinemia of the immunoglobulin (Ig)G kappa (κ) type. It is clinically characterized by yellowish red-to-brown indurated often ulcerating nodules or plaques that usually involve the periorbital regions of the elderly. We report an atypical case of NXG affecting on...
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An 82-year-old woman presented with a 9-month history of multiple, well-defined skin lesions on her neck and upper chest, progressively increasing in size. Histological examination of a skin biopsy showed a regular epidermis. In the dermis, granulomatous changes with central necrobiosis were found which extended focally into the subcutaneous fat. The necrobiotic areas were surrounded by Touton ...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2016
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2015.5151